Prothena

Prothena

Biotechnology
Prothena Corp PLC is a clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. The company's clinical pipeline of antibody-based product candidates targets a range of indications, including Amyloid Light-chain (AL) amyloidosis (NEOD001), Parkinson's disease and other related synucleinopathies (PRX002), and inflammatory diseases, including ATTR amyloidosis [Coramitug (PRX004)], Alzheimer’s disease (PRX123), Neurodegeneration (PRXPRX019), and Others.

$434.8M

Market Cap • 10/30/2026

2012

(14 years)

Founded

2012

(14 years ago)

IPO

NASDAQ

Listing Exchange

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United States

Country

Valuation

P/B

1,5

P/S

8

P/EBITDA

—

P/OCF

—

P/FCF

—

P/E

—

BVPS

5,6

EPS

—

Market Cap

Market Cap

434,8M

EV

153,6M

EV/Revenue

2,8

EV/EBITDA

-2,8

EV/EBIT

-2,8

Payout

Dividend Per Share

0

Dividend Yield

0%

Buyback Yield

5,2%

Total Yield

5,2%

Payout

0%

Retained Earnings

-1,3B

Profitability

Gross Margin

100%

EBITDA Margin

—

EBIT Margin

—

Net Margin

—

D&A/EBITDA

0%

R&D/Revenue

119,1%

Capex/Revenue

1,2%

Capex/D&A

80%

Capex/OCF

-1,1%

SBC/OCF

—

% PPE

3%

% Goodwill

0%

ROE

—

ROIC

—

Growth

CAGR Revenue 5Y

-2,1%

CAGR Op. Income 5Y

-3,2%

CAGR Net Income 5Y

-9%

CAGR EPS 5Y

-15,1%

CAGR OCF 5Y

11,1%

Leverage

N.D./EBITDA

5,1

Debt/Equity

0%

Current Ratio

25

Quick Ratio

24,7

Interest Coverage

—

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