Septerna

Septerna

Biotechnology
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.

$1.8B

Market Cap • 9/11/2026

2019

(7 years)

Founded

2024

(2 years ago)

IPO

NASDAQ

Listing Exchange

Flag of United States

United States

Country

Valuation

P/B

4,5

P/S

17,8

P/EBITDA

P/OCF

16,6

P/FCF

16,7

P/E

BVPS

8,6

EPS

Market Cap

Market Cap

1,8B

EV

1,4B

EV/Revenue

14,2

EV/EBITDA

-33,6

EV/EBIT

-32,3

Payout

Dividend Per Share

0

Dividend Yield

0%

Buyback Yield

-1%

Total Yield

-1%

Payout

0%

Retained Earnings

-188,9M

Profitability

Gross Margin

100%

EBITDA Margin

EBIT Margin

Net Margin

D&A/EBITDA

0%

R&D/Revenue

122,2%

Capex/Revenue

0,9%

Capex/D&A

55,2%

Capex/OCF

0,9%

SBC/OCF

15,4%

% PPE

4,3%

% Goodwill

0%

ROE

ROIC

Leverage

N.D./EBITDA

8,3

Debt/Equity

0%

Current Ratio

5

Quick Ratio

4,8

Interest Coverage

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