Spero Therapeutics

Spero Therapeutics

Pharmaceuticals
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

$68.1M

Market Cap • 10/7/2026

2013

(13 years)

Founded

2017

(9 years ago)

IPO

NASDAQ

Listing Exchange

Flag of United States

United States

Country

Valuation

P/B

1,5

P/S

1,4

P/EBITDA

11,3

P/OCF

3,5

P/FCF

3,5

P/E

10,6

BVPS

0,8

EPS

0,1

Market Cap

Market Cap

68,1M

EV

19,4M

EV/Revenue

0,4

EV/EBITDA

3,2

EV/EBIT

3,2

Payout

Dividend Per Share

0

Dividend Yield

0%

Buyback Yield

0%

Total Yield

0%

Payout

0%

Retained Earnings

-467,8M

Profitability

Gross Margin

100%

EBITDA Margin

12,8%

EBIT Margin

12,8%

Net Margin

16,8%

D&A/EBITDA

0%

R&D/Revenue

43,7%

Capex/Revenue

0%

Capex/D&A

0%

Capex/OCF

0%

SBC/OCF

20,4%

% PPE

2%

% Goodwill

0%

ROE

20,5%

ROIC

57,4%

Growth

CAGR Revenue 5Y

20,7%

Leverage

N.D./EBITDA

—

Debt/Equity

0%

Current Ratio

6,1

Quick Ratio

6

Interest Coverage

—

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